Loop Diuretics

Furosemide
API Manufacturer

Premium Quality IP Grade, BP Grade, USP Grade, EP Grade Furosemide | GMP Certified Facility | Global Supplier

Furosemide is a potent loop diuretic (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid) that inhibits the Na+/K+/2Cl– cotransporter in the thick ascending limb of the loop of Henle, leading to rapid diuresis.

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Enhanced Bioavailability

Rapid onset of action (peak effect within 1-2 hours orally, 5 minutes IV)

Available Grades
IPBPUSPEP
CAS Number54-31-9
Shelf Life60months
Product Details

Product Overview

Furosemide is a potent loop diuretic (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid) that inhibits the Na+/K+/2Cl– cotransporter in the thick ascending limb of the loop of Henle, leading to rapid diuresis.

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Key Benefits

Rapid onset of action (peak effect within 1-2 hours orally, 5 minutes IV)
Potent diuresis for severe fluid retention
Well-established safety and efficacy profile
Effective in both acute and chronic conditions
Multiple formulation options (oral, IV, IM)
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Physical Properties

Appearance:
Almost white crystalline powder
Molecular Formula:
C12H11ClN2O5S
Molecular Weight:
330.74 g/mol
Solubility:
Soluble in acetone, sparingly soluble in ethanol (95%), insoluble in water, dissolves in dilute aqueous solutions of alkali hydroxides
Standards:
IP GradeBP GradeUSP GradeEP Grade
Quality Standards

Technical Specifications

Comprehensive analytical specifications ensuring pharmaceutical-grade quality and consistency.

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Quality Parameters

assay
≥ 98.5% and ≤ 101.0% (on dried basis)
moisture
≤ 0.5% (loss on drying at 105°C for 3 hrs)
heavy Metals
≤ 20 ppm
residue On Ignition
≤ 0.10% (sulphated ash)
melting Point
218°C - 220°C
appearance
Almost white crystalline powder
solubility
Soluble in acetone, sparingly soluble in ethanol (95%), insoluble in water, dissolves in dilute aqueous solutions of alkali hydroxides
identification
Complies (melting point and IR spectroscopy)
chlorides
≤ 250 ppm
sulphates
≤ 300 ppm
related Substances
Unknown impurities ≤ 0.25%, Total impurities ≤ 0.50%
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Identification Codes

CAS Number:
54-31-9
HSN Code:
3004.90.99
CID Code:
3440
ATC Code:
C03CA01
DrugBank ID:
DB00695
Usage Applications

Applications & Uses

Comprehensive applications across pharmaceutical, nutraceutical, and industrial sectors.

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Cardiovascular Medicine

Management of congestive and chronic heart failure
Treatment of acute pulmonary edema
Adjunct in hypertension therapy
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Nephrology & Urology

Management of nephrotic syndrome and renal disease–related edema
Acute renal failure fluid support

Critical Care Medicine

ICU fluid management
Treatment of cerebral and pulmonary edema
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Hepatology

Ascites management in liver cirrhosis
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Research & Development

Pharmacological and pharmacokinetic studies
Formulation development and compatibility assessment
Safety Information

Safety Data Sheet

Comprehensive safety information for proper handling, storage, and emergency procedures.

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First Aid Measures

💨Inhalation:

Move to fresh air; seek medical attention if symptoms persist.

🍽️Ingestion:

Rinse mouth; do not induce vomiting; seek immediate medical attention.

Skin Contact:

Wash skin with water for at least 15 minutes; remove contaminated clothing.

👁️Eye Contact:

Rinse eyes with water for at least 15 minutes; seek medical attention if irritation continues.

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Fire-Fighting Measures

Flammability:Non-flammable solid; use standard extinguishing media.
Combustion Products:May decompose to yield sulfur oxides under extreme heat.
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Personal Protection

Standard:Wear safety goggles, gloves, and dust respirator.
Large Spill:Full protective suit, splash goggles, self-contained breathing apparatus, gloves, and boots.
Technical Data

Technical Information

Detailed chemical nomenclature and molecular information for research and regulatory purposes.

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IUPAC Names

Standard pharmaceutical nomenclature

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Synonyms

Furosemide
⚛️

Molecular Information

C12H11ClN2O5S
Molecular Formula
330.74 g/mol
Molecular Weight
3322
ChemSpider ID
Key Benefits

Leading Furosemide
Manufacturer in India

Ambition Pharma delivers superior bioavailability and enhanced absorption through our advanced manufacturing processes.

Enhanced Bioavailability

Rapid onset of action (peak effect within 1-2 hours orally, 5 minutes IV)

🎯

Reduced Side Effects

Potent diuresis for severe fluid retention

📈

Faster Results

Well-established safety and efficacy profile

💧

Superior Quality

Effective in both acute and chronic conditions

Why Choose Us

Premium QualityManufacturing

Furosemide Excellence

Discover why leading pharmaceutical companies trust our advanced manufacturing capabilities and commitment to quality excellence.

🔬

Advanced Synthesis

GMP Certified

State-of-the-art manufacturing processes ensuring consistent quality and purity standards.

⚗️

Quality Assurance

ISO 9001:2015

Rigorous testing protocols and quality control measures at every production stage.

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Global Compliance

GMP

Meeting international regulatory standards for pharmaceutical manufacturing.

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Analytical Testing

HPLC/LCMS

Comprehensive analytical testing using advanced instrumentation and methods.

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Scalable Production

Multi-Scale

Flexible manufacturing capabilities from pilot scale to commercial production.

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Documentation

DMF Support

Complete regulatory documentation and technical support for global markets.

Ready to Experience Premium Quality?

Join leading pharmaceutical companies worldwide who trust our advanced manufacturing capabilities and commitment to excellence.

FAQ Section

Frequently AskedQuestions

Furosemide Manufacturing

Common queries about our furosemide manufacturing capabilities, specifications, and quality assurance processes.

A

The assay content is ≥ 98.5% and ≤ 101.0% on dried basis, as per IP specifications.

A

The product appears as almost white crystalline powder with melting point 218°C-220°C, loss on drying ≤ 0.5% (at 105°C for 3 hrs), and sulphated ash ≤ 0.10%.

A

Each shipment includes CoA, DMF/CEP/USDMF references, GMP and ISO certificates, and Certificate of Origin.

A

Soluble in acetone, sparingly soluble in ethanol (95%), insoluble in water, dissolves in dilute aqueous solutions of alkali hydroxides.

A

Our Furosemide has a shelf life of 60 months (5 years) from date of manufacture when stored properly at room temperature (15–25 °C) in a dry place, protected from light and moisture.

A

Available grades include IP, BP, USP, and EP.

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Furosemide API

Get competitive pricing from India's leading Furosemide manufacturer. We supply pharmaceutical grade APIs with international standards. GMP certified facility with global delivery.

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Multiple Grades

IP, BP, USP, EP pharmacopeial standards available

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GMP Certified

GMP compliant manufacturing facility

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Global Supply

Worldwide pharmaceutical API distribution

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